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Clinical Research​

Retrospective Clinical Studies: ​

  •  Identify specific genes or proteins as biomarkers in glioblastoma tumors or biological fluids (blood or urine) to inform about patient outcome (prognosis) and predict response to treatment. Further validation in a clinical trial is required.

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Clinical Trials: ​

  •  Evaluate the safety and efficacy of treatment in patients, while integrating scientific, clinical, statistical and ethical approaches in a highly regulated clinical setting.​

  •  Eligible Patients sign an informed consent form to participate to the clinical trial. ​

  •  The medical team monitors and evaluates side effects, tumor progression, patient survival and new biomarkers to predict response to treatment. ​

Credit: Dr. S. Sabri & Dr. B. Abdulkarim ​Research Laboratories​

Treatment Strategies Tested alone or in Combination in Clinical Trials: ​

  • Chemotherapy and different modalities of radiotherapy​

  • Targeted therapies to inhibit specific cellular targets or interactions with the tumor microenvironment​

  • Immunotherapy to direct the immune system towards attacking glioblastoma cancer cells.​

  • Repurposing drugs clinically approved for another disease for a new use in glioblastoma based on the ability to inhibit a survival pathway in the tumor. ​

  • Natural products to prove efficacy and safety before approval. 

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