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Glioblastoma Symptoms and Diagnosis

Glioblastoma is classified as a high-grade or grade IV brain tumor. Glioblastoma tumors start most often in the cerebral hemispheres. Symptoms vary based on the tumor location and the extent of swelling in the brain. They can include worsening headaches, seizures, vision changes, difficulty speaking, confusion or memory loss, or personality changes.

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Credit: iStock

Glioblastoma Diagnosis: ​

  • Imaging using CT or MRI scans detects a tumor with its exact location in the brain. ​

  • MRI with contrast showing a strong contrast enhancement and central necrosis indicates a glioblastoma tumor.​

  • Analysis of a tumor tissue sample in a neuropathology lab validates glioblastoma diagnosis using an international classification for brain tumor types, and tumor grade. ​

  • Further molecular testing guides treatment decision to participate in a clinical trial.

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